Thermo Scientificâ„¢ SM(PEG)4 (PEGylated SMCC crosslinker)
Manufacturer Code - 22104
The SM(PEG)n reagents are six crosslinkers that have identical amine- and sulfhydryl-reactive groups but differ in length as a result of spacer arms composed of different numbers of ethylene glycol units. Their structures (shown below) have the form NHS-(PEG)n-Maleimide, where n represents 2, 4, 6, 8, 12 or 24 polyethylene glycol (PEG) units. Each SM(PEG)n reagent is produced at the specified length without contamination from analogs of other lengths.The availability of this set of reagents makes it possible to optimize crosslinking experiments to obtain the best conjugate efficiency and function for the intended application or analysis method. Considered together with AMAS (Part No. 22295) and the popular SMCC (Part No. 22360), these reagents allow for amine-to-sulfhydryl crosslinking across spaces ranging from 4.4 to 95.2Å. In addition, the hydrophilic PEG content of SM(PEG)n reagents adds to the aqueous solubility of these crosslinkers and their conjugates. PEG is also less immunogenic than other types of crosslinker spacers, making these reagents ideal for immunogen preparation.
Highlights:
NHS-PEG2-Maleimide
NHS-PEG4-Maleimide
NHS-PEG6-Maleimide
NHS-PEG8-Maleimide
NHS-PEG12-Maleimide
LabelingMethod | Chemical Labeling |
Unit | 0 |
Qualifier | cl_MTS_Diagnostics_ProteinChemistryReagentsandKits_CrosslinkingandProteinModification |
Productsapid | 22104 |
Language | en |
Valueposition | 0 |
Product Name | Thermo Scientific™ SM(PEG)4 (PEGylated SMCC crosslinker) |
---|---|
SKU | FIS2210-4 |
Visibility | Catalog, Search |
UOM | EA |
Brand | Thermo Scientific |
Lead time if no stock (days) | 49 |
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